Skip to content

Use of Ex Vivo Lung Perfusion (EVLP) in Reconditioning Marginal Donor Lungs for Transplantation

Lung Transplant

The overall objective of this study is to evaluate the clinical effectiveness of the novel technique of donor EVLP in increasing lung transplant activity by allowing previously unusable donor lungs to be safely used in clinical lung transplantation. Furthermore, to utilize the EVLP technique in research settings thus allowing the evaluation of inflammatory molecules (biomarkers) that would benefit a successful pre-conditioning and increase knowledge of the lungs inflammatory response before transplantation.

null

Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    18 to 65

Critères de participation

Inclusion Criteria:

* Adult patients (aged 18 years and over).
* Patients already on or added to the active waiting list for first lung transplant.
* Patients providing informed consent for participation in the study at the time of study commencement or time of listing for transplant.
* Patients' re-confirmation informed consent for the study on the day of the lung transplant.

Exclusion Criteria:

* Patients aged less than 18 years.
* Patients not providing informed consent for the study.
* Patients not in possession of patient information sheets for the study prior to the day of lung transplant.
* Patients' not re-confirming consent for the study on the day of lung transplant.
* Patients requiring invasive mechanical ventilation, extracorporeal membrane oxygenation (ECMO) support.

Lieu de l'étude

Centre Hospitalier de l'Université de Montréal (CHUM)
Centre Hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec
Canada

Contactez l'équipe d'étude

Backup Contact

Basil Nasir, MD

[email protected]
514-890-8000
Primary Contact

Ahmed Menaouar, PhD

[email protected]
514-890-8000
Étude parrainée par
Centre hospitalier de l'Université de Montréal (CHUM)
Participants recherchés
Plus d'informations
ID de l'étude: NCT02235610