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Exercise and Cardiac Stunning During HD

Hemodialysis | End-stage Kidney Disease

The purpose of this study is to determine the effect of a 12-week cycling during hemodialysis program on hemodialysis-induced myocardial stunning in adult individuals receiving hemodialysis.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Adults greater than or equal to 18 years old (no upper age limit); who are greater than; 3 months after starting maintenance hemodialysis
* No expected change in dialysis modality, elective surgery or relocation outside of study site during the intervention period (16 weeks)
* Assessed to be safe and able to exercise by the hemodialysis unit nephrologist
* Able to communicate in English and provide written informed consent
* Must be dialyzing thrice weekly

Exclusion Criteria:

* Acute coronary syndrome in the past 3 months
* Unstable arrhythmia
* Shortness of breath at rest or with minimal activity (NYHA Class 4)
* Symptomatic hypoglycemia (\>2x/week in week prior to enrolment)
* Participating in clinical intradialytic cycling program in last 3 months (if a clinical program exists)

Study Location

University of Manitoba Department of Internal Medicine
University of Manitoba Department of Internal Medicine
Winnipeg, Manitoba
Canada

Contact Study Team

St. Pauls Hospital
St. Pauls Hospital
Vancouver, British Columbia
Canada

Contact Study Team

University of Alberta Department of Internal Medicine
University of Alberta Department of Internal Medicine
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Stephanie Thompson, MD, PhD

[email protected]
780-492-4228
University of Calgary Cumming School of Medicine Department of Internal Medicine
University of Calgary Cumming School of Medicine Department of Internal Medicine
Calgary, Alberta
Canada

Contact Study Team

Western University
Western University
London, Ontario
Canada

Contact Study Team

Primary Contact

Jarrin Penny, RN

Study Sponsored By
University of Manitoba
Participants Required
More Information
Study ID: NCT04877041