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COMPASS-ND

COMPASS-ND is an observational study of people with various types of mild cognitive complaints, people with Parkinson's disease, as well as healthy people. The study collects clinical, neuropsychological, and MRI imaging data as well as blood, saliva, and urine samples. Willing participants may undergo additional tests including: a take home sleep study, fecal sample collection, and brain donation. Annual telephone checks will be conducted and the baseline procedures will be repeated after 2 years.

The major goals of the study are:
To learn about who is at risk of developing dementia
To determine how early dementia can be detected
To find out what tests are most effective at detecting dementia

http://ccna-ccnv.ca/compass-nd-study/

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Participation Requirements

  • Sex:

    Female, Male

  • Eligible Ages:

    50 to 90

Participation Criteria

Inclusion Criteria:
All participants must:
- be able to understand, read, write, and speak everyday English with ease
- have a reliable study partner to accompany them to study visits, and to participate in interviews about the participant as well complete questionnaires about the participant
- live within 2 hours of the University of Alberta Hospital
- be willing to undergo an MRI of the head (must not have concerns about claustrophobia)
Healthy controls (those without any memory concerns) must be between 60 and 90 years old. Participants with memory concerns must be between 60 and 90 years old, and have a diagnosis from their family doctor or a neurologist of mild cognitive impairment or mild vascular cognitive impairment. Participants with Parkinson's disease must be between 50 and 90 years old.
Exclusion Criteria:
Some implanted medical devices are unsafe for the MRI.
If the participant drinks more than 5 servings of alcohol per day or engages in regular use of illegal drugs, they will not be suitable for this study.
Participants who have had a stroke with cognitive impairment in the last year are not able to enroll in this study.
Participants with untreated psychiatric illnesses are not able to participate in this study.

Study Location

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Krista Nelles

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780-248-2043
Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: Pro00061456