Skip to content

Functional Imaging of Baby Brains

Hypoxic-Ischemic Encephalopathy | Hypoxia-Ischemia, Brain | Hypoxia Ischemia, Cerebral | Hypoxia Neonatal

Infants are at risk of developing motor and cognitive neurodevelopmental disabilities as a sequelae to hypoxic-ischemic brain injury during the perinatal period. It is an ongoing challenge to predict the severity and extent of future developmental impairment during the neonatal period. This study will help test the feasibility of conducting a large-scale study that evaluates the role of diffuse optical tomography as a bedside neuroimaging tool in complementing the prognostic value of conventional and diffusion weighted MRI for predicting neurodevelopmental outcome in neonates with perinatal hypoxic-ischemic brain injury.

null

Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    1 to 15

Participation Criteria

Inclusion Criteria:

* Newborns admitted to the McMaster Children's Hospital Neonatal Intensive Care Unit with the diagnosis of hypoxic-ischemic encephalopathy will be considered for this study
* Gestational age of 35 weeks or greater
* Birth weight more than 1.8 Kg

Exclusion Criteria:

(i) suspected or confirmed congenital malformations, (ii) chromosomal anomalies, (iii) inborn errors of metabolism, (iv) congenital infections, (v) neonatal encephalopathy other than HIE, (vi) baby requires respiratory support in the form of CPAP, Mechanical ventilation, high flow nasal cannula and (vii) scalp injury or non-intact skin surface in the scalp

Study Location

McMaster Children's Hospital
McMaster Children's Hospital
Hamilton, Ontario
Canada

Contact Study Team

Backup Contact

Ipsita Goswami Principal Investigator, MD

[email protected]
9055212100
Primary Contact

Heather Johnson Clinical Research Coordinator

[email protected]
9055212100
Backup Contact

Gabriel Xiao Assistant Professor, PhD

Study Sponsored By
Hamilton Health Sciences Corporation
Participants Required
More Information
Study ID: NCT05514665