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Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery

Elective Colon Surgery

The REaCT NSQIP will compare oral antibiotics vs. no antibiotics, which are two standards of care treatments for preoperative preparation of the bowel prior to colorectal surgery

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Patients undergoing elective, non-emergency colon, resection surgery or abdominal perineal resection and no other requirements exists for a mechanical bowel preparation (as determined by the operating surgeon)
* 18 years of age or older
* Able to provide oral consent

Exclusion Criteria:

* Contraindication to the oral antibiotics, including allergies or adverse reactions to either metronidazole or neomycin
* Undergoing a rectal resection with a planned anastomosis (these patients will all receive MBP)
* Emergency surgery where no opportunity to administer preoperative oral antibiotics exists
* Requirement for a MBP (i.e. rectal resection with pelvic anastomosis, intraoperative colonoscopy, or at the discretion of the treating surgeon

Study Location

The Ottawa Hospital Cancer Centre
The Ottawa Hospital Cancer Centre
Ottawa, Ontario
Canada

Contact Study Team

The Queen Elizabeth II Health Sciences Centre
The Queen Elizabeth II Health Sciences Centre
Halifax, Nova Scotia
Canada

Contact Study Team

Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre
Toronto, Ontario
Canada

Contact Study Team

Queensway Carleton Hospital
Queensway Carleton Hospital
Ottawa, Ontario
Canada

Contact Study Team

Renfrew Victoria Hospital
Renfrew Victoria Hospital
Renfrew, Ontario
Canada

Contact Study Team

Study Sponsored By
Ottawa Hospital Research Institute
Participants Required
More Information
Study ID: NCT03663504