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Improving Pain Disability With the Use of Oral Cannabinoids

Opioid Use | Chronic Pain | Cannabis

The investigators are conducting a pilot (i.e. a small study) in order to find out the effectiveness and safety of medical cannabis in the management of chronic pain. At the end of this 3 month study, investigators will gather information on how easy it is for patients to enroll and complete the entire study. The results of this pilot study will help the study team design a larger randomized controlled trial.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    25 and up

Participation Criteria

Inclusion Criteria:

1. Age ≥ 25 years
2. Able to understand and read English
3. Experiencing chronic, non-palliative pain

Exclusion Criteria:

1. Use of nabilone, nabiximols or cannabis in the 30 days preceding study recruitment
2. Known allergy to cannabis or any cannabinoid
3. Serious ongoing medical issues (i.e., lung, liver, kidney or heart disease) that in the opinion of the Investigator would compromise the safety of the patient
4. Current uncontrolled serious mental disorders such as schizophrenia, or psychosis
5. Currently pregnant or breast-feeding (a negative urine pregnancy test must be obtained for women of child bearing potential during pretreatment evaluation)
6. Men and women planning to start a family in the next 12 weeks
7. Has declared a current alcohol or substance use disorder (excluding opioid use disorder)
8. Currently using Methadone or Buprenorphine
9. Patients who are naïve to pain treatments

Study Location

University Health Network
University Health Network
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Sonalben Thaker

[email protected]
4163404800
Backup Contact

Jo Carroll

[email protected]
4163404800
Study Sponsored By
University Health Network, Toronto
Participants Required
More Information
Study ID: NCT05351905