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Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis

ARDS, Human

Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue oxygenation (StO2) in the brain, for patients with acute respiratory distress syndrome (ARDS) in the ICU.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Adult patient admitted to the ICU
* ARDS confirmed according to the Berlin Definition
* Invasive mechanical ventilation
* Deep sedation and/or neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team
* Application of monitoring devices feasible

Exclusion Criteria:

* More than 24 hours elapsed since ICU admission
* Death is deemed imminent and inevitable during the next 24 hours
* Known allergy to a textile component of the device
* Consent declined from patient or authorized third party
* The treating clinician believes that participation in the study would not be in the best interest of the patient

Study Location

Health Sciences Centre Winnipeg
Health Sciences Centre Winnipeg
Winnipeg, Manitoba
Canada

Contact Study Team

Primary Contact

Asher Mendelson, MD PhD

[email protected]
2047878059
Study Sponsored By
University of Manitoba
Participants Required
More Information
Study ID: NCT05847634