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Predicting Dysglycemia in Individuals With Gestational Diabetes Immediately Postpartum Using Continuous Glucose Monitoring

Endocrine System Diseases | Type 2 Diabetes | Pregnancy Related | Gestational Diabetes | Glucose Metabolism...

Gestational diabetes is one of the most common medical disorders in pregnancy and is a major risk factor for the postpartum development of dysglycemia. Despite the high risk of developing dysglycemia, 50-80% of women with gestational diabetes are not receiving testing within a year postpartum. The investigators will conduct a prospective cohort study to examine the use of continuous glucose monitoring immediately postpartum to estimate the risk of maternal dysglycemia postpartum.

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Participation Requirements

  • Sex:

    FEMALE
  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Pregnant individuals age 18 and older
* Diagnosed with gestational diabetes by the Diabetes Canada guidelines (including both the preferred or alternate testing approaches) or have an HbA1c of 6.0-6.4% during pregnancy
* Have any of the following: have an elevated fasting glucose (≥ 5.3 mmol/L) on the diagnostic 75g OGTT in pregnancy; required insulin or metformin for treatment during pregnancy; body mass index (BMI) ≥ 25kg/m2, yes/no (\<27 weeks gestation BMI of ≥25 kg/m2 or ≥27 weeks gestation predicted BMI of ≥ 25 kg/m2 using (current weight in kg - 10kg)/height in meters2)
* Planned in-hospital delivery
* Able to provide informed consent
* Willingness to use the study device and complete assessments
* Have access to email in order to complete participant questionnaire through REDCap

Exclusion Criteria:

* Non-gestational diabetes (i.e. pre-existing diabetes)
* Planned x-ray, MRI or CT within 3 weeks postpartum
* Has an implantable medical device (ex. pacemaker)
* On medications known to affect glucose metabolism (for example glucocorticoids, metformin etc.)
* On medications which may interfere with the Freestyle Libre 2 accuracy (for example Vitamin C \>1000mg/day)
* Unable to speak and understand French or English
* Unable to consent or declined informed consent

Study Location

Universite Laval
Universite Laval
Quebec City, Quebec
Canada

Contact Study Team

Backup Contact

Julie-Catherine Coll, MD

Primary Contact

Patricia Lemieux, MD

Mount Sinai Hospital
Mount Sinai Hospital
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Denice S Feig, MD

Backup Contact

Sonia Masuta, BSc

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Primary Contact

Lois E Donovan, MD

Backup Contact

Jane Booth, MSc

University of Manitoba
University of Manitoba
Winnipeg, Manitoba
Canada

Contact Study Team

Backup Contact

Sarah Sigurdson, BSc

[email protected]
2047893359
Primary Contact

Jennifer Yamamoto, MD

[email protected]
2047893697
Study Sponsored By
University of Manitoba
Participants Required
More Information
Study ID: NCT04972955