Predicting Dysglycemia in Individuals With Gestational Diabetes Immediately Postpartum Using Continuous Glucose Monitoring
Endocrine System Diseases | Type 2 Diabetes | Pregnancy Related | Gestational Diabetes | Glucose Metabolism...Gestational diabetes is one of the most common medical disorders in pregnancy and is a major risk factor for the postpartum development of dysglycemia. Despite the high risk of developing dysglycemia, 50-80% of women with gestational diabetes are not receiving testing within a year postpartum. The investigators will conduct a prospective cohort study to examine the use of continuous glucose monitoring immediately postpartum to estimate the risk of maternal dysglycemia postpartum.
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Participation Requirements
-
Sex:
FEMALE -
Eligible Ages:
18 and up
Participation Criteria
Inclusion Criteria:
* Pregnant individuals age 18 and older
* Diagnosed with gestational diabetes by the Diabetes Canada guidelines (including both the preferred or alternate testing approaches) or have an HbA1c of 6.0-6.4% during pregnancy
* Have any of the following: have an elevated fasting glucose (≥ 5.3 mmol/L) on the diagnostic 75g OGTT in pregnancy; required insulin or metformin for treatment during pregnancy; body mass index (BMI) ≥ 25kg/m2, yes/no (\<27 weeks gestation BMI of ≥25 kg/m2 or ≥27 weeks gestation predicted BMI of ≥ 25 kg/m2 using (current weight in kg - 10kg)/height in meters2)
* Planned in-hospital delivery
* Able to provide informed consent
* Willingness to use the study device and complete assessments
* Have access to email in order to complete participant questionnaire through REDCap
Exclusion Criteria:
* Non-gestational diabetes (i.e. pre-existing diabetes)
* Planned x-ray, MRI or CT within 3 weeks postpartum
* Has an implantable medical device (ex. pacemaker)
* On medications known to affect glucose metabolism (for example glucocorticoids, metformin etc.)
* On medications which may interfere with the Freestyle Libre 2 accuracy (for example Vitamin C \>1000mg/day)
* Unable to speak and understand French or English
* Unable to consent or declined informed consent
Study Location
Universite Laval
Universite LavalQuebec City, Quebec
Canada
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Julie-Catherine Coll, MD
Patricia Lemieux, MD
Mount Sinai Hospital
Mount Sinai HospitalToronto, Ontario
Canada
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Denice S Feig, MD
Sonia Masuta, BSc
University of Calgary
University of CalgaryCalgary, Alberta
Canada
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Lois E Donovan, MD
Jane Booth, MSc
University of Manitoba
University of ManitobaWinnipeg, Manitoba
Canada
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- Study Sponsored By
- University of Manitoba
- Participants Required
- More Information
- Study ID:
NCT04972955