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Cardiac Rehabilitation for Cardiovascular Risk Reduction in People With Severe and Persistent Mental Illness

Cardiovascular Prevention | Mental Illness Persistent

The goal of this prospective, randomized trial is to explore the link between cardiovascular disease and mortality in individuals with severe and persistent mental illness (SPMI). The main question it aims to answer is: Is a primary prevention cardiac rehabilitation intervention feasible and effective at reducing cardiovascular risk in people with a primary psychotic disorder or bipolar disorder?"

Participants will undergo a multi-component primary prevention intervention program. Researchers will compare with a control group to see if cardiovascular risk reduction is attained.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    30 to 59

Participation Criteria

Inclusion Criteria:

* Age ≥ 30 to 59 years old
* Psychiatric diagnosis of schizophrenia, schizoaffective disorder, or bipolar I disorder
* 2 or more cardiac risk behaviors or conditions: smoking, obese, hypertension, diabetes, metabolic syndrome, dyslipidemia, obstructive sleep apnea
* 10-year Framingham cardiovascular risk score of ≥ 10% (intermediate risk)
* Willing to participate in cardiac rehabilitation program

Exclusion Criteria:

* Psychiatric instability, as judged by treating psychiatrist
* Distance from cardiac rehabilitation centre that would preclude participation
* Unsafe to participate in the cardiac rehabilitation intervention, as judged by the cardiology assessment
* Pregnant
* Known coronary artery disease, cerebrovascular disease, or peripheral vascular disease
* Court ordered mandatory or tutor

Study Location

Jewish General Hospital/Lady Davis Institute
Jewish General Hospital/Lady Davis Institute
Montréal, Quebec
Canada

Contact Study Team

Primary Contact

Michael J Goldfarb, MD MSc

[email protected]
514-340-8222
Study Sponsored By
Lady Davis Institute
Participants Required
More Information
Study ID: NCT05659498