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PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism

Venous Thromboembolism | Pregnancy Related

The PREP and GO study is an international multicentre prospective cohort evaluating anticoagulation management strategies around labor and delivery and the postpartum period.

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Participation Requirements

  • Sex:

    FEMALE
  • Eligible Ages:

    18 to 60

Participation Criteria

Inclusion Criteria:

* 18 years of age or older
* Requires anticoagulation during the antepartum period of pregnancy for a VTE indication, including at least one of:

1. Objectively confirmed VTE (DVT, superficial vein thrombosis \[SVT\], PE or unusual site thrombosis) diagnosed during the current pregnancy;
2. Objectively confirmed VTE diagnosed in a prior pregnancy;
3. Objectively confirmed VTE diagnosed when not pregnant;
4. Inherited or acquired thrombophilia requiring anticoagulation.
* Receiving any dose or type of LMWH during the antepartum period

Exclusion Criteria:

* Anticoagulation for a non-VTE indication, including prosthetic heart valves, atrial fibrillation, prevention of placenta-mediated pregnancy complications, or prevention of recurrent pregnancy loss (participants can be included with a diagnosis of antiphospholipid syndrome (APS) with or without thrombotic events)
* Unable to provide or declined consent.
* Home or birthing centre planned delivery.

Study Location

Foothills Medical Centre
Foothills Medical Centre
Calgary, Alberta
Canada

Contact Study Team

Primary Contact

Emily McKibbon

[email protected]
403-220-7631
Backup Contact

Leslie Skeith, MD

[email protected]
403-944-5246
Study Sponsored By
University of Calgary
Participants Required
More Information
Study ID: NCT05756244