Virtual Rehabilitation for Cancer Survivors
Lymphoma | Breast Cancer Stage II | Breast Cancer Stage III | Lymphoproliferative Disorders | Breast Cancer Stage...Pragmatic hybrid type 1 effectiveness-implementation (E-I) trial of a virtual cancer rehabilitation program: The study team will conduct a multi-center hybrid type I effectiveness-implementation study to examine the clinical effectiveness and implementation potential of an 8-week multidimensional virtual cancer rehabilitation intervention (CaRE@Home) for cancer survivors with identified cancer-related impairments on level of overall disability (primary outcome) and patient reported physical and social functioning, anxiety, work status, quality of life, and physiologic changes (secondary outcomes). The study team will conduct a multi-centre pragmatic randomized controlled trial (RCT) (Vancouver, Toronto, Saint John and St. John's) to evaluate effectiveness and using the CIFR, the study team will identify potential factors that may affect successful implementation and integration of CaRE@Home in different cancer settings.
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Participation Requirements
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Sex:
ALL -
Eligible Ages:
18 and up
Participation Criteria
Inclusion Criteria:
* 1) Age 18 years or older
* 2) Diagnosed with breast (stage 0-III), colorectal (stage I-III), head and neck (stage I-III), or lymphoma/lymphoproliferative disorder (excluded: recurrent, refractory, progressive, received or planning to receive transplant)
* 3) Completed a primary treatment (i.e. surgery and/or radiation and/or systemic therapy of any kind) within the last 24 months
* 4) If patients received systemic therapy of a fixed duration with adjuvant/curative intent, the main part should be completed, but patients are eligible if on primary, maintenance, or other adjuvant systemic therapy (e.g. eligible while on trastuzumab, immunotherapy, rituximab, oral endocrine or targeted therapy - ie ibrutinib). Indolent non-curative lymphoma patients are eligible if they have response to systemic therapy
* 5) Communicate sufficiently in English to complete intervention and questionnaires
* 6) Willing to be randomized and participate in the intervention and in-person assessments; 6) Internet access
* 7) An indication for cancer rehabilitation (WHO-DAS score \>5).
Exclusion Criteria:
* 1) Impaired functional status that would preclude rehabilitation (PRFS \>3)
* 2) Indication of major depressive disorder (PHQ-2 \>3)
* 3) Diagnosis of neurological disease or condition significantly limiting cognitive functioning, such as language or memory (e.g., Alzheimer's disease or other dementia, severe traumatic brain injury);
* 4) Conditions or current injuries which are not appropriate for distance based exercise
Study Location
Princess Margaret Cancer Centre
Princess Margaret Cancer CentreToronto, Ontario
Canada
Contact Study Team
- Study Sponsored By
- University Health Network, Toronto
- Participants Required
- More Information
- Study ID:
NCT05898789