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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis | MASH - Metabolic Dysfunction-Associated Steatohepatitis

This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.

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Conditions de participation

  • Sexe:

    ALL

  • Âges admissibles:

    18 to 80

Critères de participation

Inclusion Criteria:

* Cohort 1: Biopsy proven compensated cirrhosis (fibrosis stage 4) due to NASH/MASH
* Cohort 2: Biopsy proven or non-invasively diagnosed compensated cirrhosis (fibrosis stage 4) due to NASH/MASH

Exclusion Criteria:

* Other causes of liver disease based on medical history and/or liver histology and/or central laboratory results
* Type 1 diabetes or unstable Type 2 diabetes
* Any current or prior history of decompensated liver disease

Other inclusion and exclusion criteria may apply

Lieu de l'étude

Akero Clinical Study Site
Akero Clinical Study Site
Edmonton, Alberta
Canada

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Primary Contact

Akero Site 0501

Akero Clinical Study Site
Akero Clinical Study Site
Vaughan, Ontario
Canada

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Akero Clinical Study Site
Akero Clinical Study Site
Montreal, Quebec
Canada

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Primary Contact

Akero Site 0506

Akero Clinical Study Site
Akero Clinical Study Site
Toronto, Ontario
Canada

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Primary Contact

Akero Site 0502

Akero Clinical Study Site
Akero Clinical Study Site
Terrebonne, Quebec
Canada

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Primary Contact

Akero Site 0505

Étude parrainée par
Akero Therapeutics, Inc
Participants recherchés
Plus d'informations
ID de l'étude: NCT06528314