Rehabilitation for People With Advanced Cancer
Advanced Breast Cancer | Advanced Colorectal Cancer | Cancer RehabilitationThe proposed study is a Phase II, feasibility, randomized controlled preference based study. This will be conducted in Vancouver and Toronto and includes breast and colorectal cancers.
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Participation Requirements
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Sex:
ALL -
Eligible Ages:
18 and up
Participation Criteria
Inclusion Criteria:
* Age 18 years or older
* Diagnosed with locally advanced incurable or metastatic breast or colorectal cancer
* Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
* Fully independent with ambulation and transfers with or without ambulatory assistance
* Palliative Performance score of \>70 (moderate predictive power estimating life expectancy \>6 months)
* Receiving first or second line anti-cancer treatments in the metastatic / incurable setting (a relative proxy for expected survival \>6 months)
* Medical clearance to participate from treating physician
Exclusion Criteria:
* Wheelchair level community ambulation
* Moderate or severe non-cancer pain (\>6 out of 10 on visual analog scale)
* Moderate or severe cancer bone pain (\>Gr 2 bone pain (i.e., moderate pain limiting instrumental ALDs or worse) as measured on CTCAE (see below))
* Severe or uncontrolled depressive symptoms (\>20 on PHQ-9)
* Known neurological conditions influencing cognition and preventing safe or appropriate engagement with self-management and exercise recommendations (e.g., dementia, traumatic brain injury, or brain metastasis influencing cognition or causing moderate-to-severe motor-sensory-coordination). Best determined by the referring physician or nurse practitioner.
* Unable to communicate sufficiently in English to complete intervention, questionnaires, and consent.
* Unwillingness to be randomized, participate in a group intervention, or attend individual physical assessments.
* Inability to operate videoconferencing if preference is virtual programming.
Study Location
Princess Margaret Cancer Centre
Princess Margaret Cancer CentreToronto, Ontario
Canada
Contact Study Team
- Study Sponsored By
- University Health Network, Toronto
- Participants Required
- More Information
- Study ID:
NCT05424068