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Longitudinal Study to Investigate Different Transcranial Electrical Stimulation

Dementia; Degenerative, Dementia Mixed

This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday). The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur for 4 weeks, then 12 weeks of no treatment (wash-out period), repeated for each tES treatment type. Participants have the option of having their choice of music in the background while they perform cognitive exercises.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    50 and up

Participation Criteria

Inclusion Criteria:

* ability to read, write and speak English fluently
* MoCA score between 5 and 24

Exclusion Criteria:

* Being diagnosed with Parkinson's disease, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder.
* Having a history of epileptic seizures or epilepsy
* Inability to adequately communicate in English
* Impaired vision or hearing severe enough to impair performance in cognitive tests
* Current substance abuse disorder
* Currently participating in another therapeutic study for dementia
* Plan to change the medication during any treatment period (5 weeks including the pre-post assessments)

Study Location

Riverview Health Centre
Riverview Health Centre
Winnipeg, Manitoba
Canada

Contact Study Team

Primary Contact

Shelly Rempel-Rossum

[email protected]
204-789-3389
Backup Contact

Zahra Moussavi

2044786163
Study Sponsored By
University of Manitoba
Participants Required
More Information
Study ID: NCT06877312