A Combined Multidomain Intervention to Prevent Cognitive Decline Associated with Cardiovascular Risk Factors.
Aging | Cardiovascular Risk FactorThe ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.
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Participation Requirements
-
Sex:
ALL -
Eligible Ages:
60 and up
Participation Criteria
Inclusion Criteria:
* Adult aged 60 and older,
* Normal or corrected vision and normal hearing for their age range,
* No cognitive impairment (Mini-Mental State Examination - MMSE ≥ 25),
* Inactive (\< 150 min of physical activity per week).
Exclusion Criteria:
* MMSE ≤ 24 or diagnosis of dementia,
* Uncontrolled psychological / psychiatric condition within the past 6 months,
* Neurological disease,
* Severe exercise intolerance,
* Respiratory disease (e.g., asthma, COPD),
* Excessive alcohol consumption (\> 15 drinks/week),
* Documented cerebral, peripheral or coronary atherosclerotic disease,
* Chronic systolic or diastolic heart failure,
* Symptomatic aortic stenosis,
* Atrial fibrillation,
* Automatic implantable defibrillator or permanent pacemaker,
* Malignant exertional arrhythmias,
* Non-cardiopulmonary limitation to exercise (e.g., arthritis).
Study Location
Preventive medicine and physical activity centre (centre EPIC), Montreal Heart Institute
Preventive medicine and physical activity centre (centre EPIC), Montreal Heart InstituteMontreal, Quebec
Canada
Contact Study Team
Anil Nigam, MD
Louis Bherer, PhD
- Study Sponsored By
- Montreal Heart Institute
- Participants Required
- More Information
- Study ID:
NCT04962061