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A Combined Multidomain Intervention to Prevent Cognitive Decline Associated with Cardiovascular Risk Factors.

Aging | Cardiovascular Risk Factor

The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    60 and up

Participation Criteria

Inclusion Criteria:

* Adult aged 60 and older,
* Normal or corrected vision and normal hearing for their age range,
* No cognitive impairment (Mini-Mental State Examination - MMSE ≥ 25),
* Inactive (\< 150 min of physical activity per week).

Exclusion Criteria:

* MMSE ≤ 24 or diagnosis of dementia,
* Uncontrolled psychological / psychiatric condition within the past 6 months,
* Neurological disease,
* Severe exercise intolerance,
* Respiratory disease (e.g., asthma, COPD),
* Excessive alcohol consumption (\> 15 drinks/week),
* Documented cerebral, peripheral or coronary atherosclerotic disease,
* Chronic systolic or diastolic heart failure,
* Symptomatic aortic stenosis,
* Atrial fibrillation,
* Automatic implantable defibrillator or permanent pacemaker,
* Malignant exertional arrhythmias,
* Non-cardiopulmonary limitation to exercise (e.g., arthritis).

Study Location

Preventive medicine and physical activity centre (centre EPIC), Montreal Heart Institute
Preventive medicine and physical activity centre (centre EPIC), Montreal Heart Institute
Montreal, Quebec
Canada

Contact Study Team

Backup Contact

Anil Nigam, MD

Backup Contact

Louis Bherer, PhD

Primary Contact

Louis Bherer, PhD

[email protected]
514-374-1480
Study Sponsored By
Montreal Heart Institute
Participants Required
More Information
Study ID: NCT04962061