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Characterizing Hemorrhage in Acute Spinal Cord Injury With MRI

Traumatic Spinal Cord Haemorrhage

The study is designed to determine whether hemorrhage within the injured spinal cord is influenced by mean arterial pressure (MAP) augmentation with vasopressors and by venous thromboembolism (VTE) prophylaxis with anticoagulants in the first two weeks following a traumatic spinal cord injury (tSCI).

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    19 and up

Participation Criteria

Inclusion Criteria:

* Acute tSCI injury involving bony spinal levels between C0 and T1
* Baseline Asia Impairment Scale (AIS) grade of A, B, or C
* Admission to study site within 24 hours of injury
* Male or female age 19 or older
* Able and willing to provide informed consent

Exclusion Criteria:

* Pathological fracture due to metabolic condition or neoplasia
* Spinal cord injury due to infection
* Presence of pacemaker, aneurysm clip or other device which is a contraindication to MRI
* BMI \> 40 and unable to fit within the MRI scanner
* Multiple life threatening injuries (ISS \>16) that make transport to MRI not in the patient's best interest
* Any condition that, at the time of admission, prevents a complete ISNCSCI assessment from being performed

Study Location

Vancouver General Hospital
Vancouver General Hospital
Vancouver, British Columbia
Canada

Contact Study Team

Primary Contact

Allan Aludino

604-875-4111
Study Sponsored By
University of British Columbia
Participants Required
More Information
Study ID: NCT04758377