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Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain

Fibromyalgia | Chronic Low-back Pain

The primary aim of this study is to document the feasibility and acceptability of an intervention consisting of pain neuroscience education and reconsolidation therapy with propranolol in adults suffering from chronic pain (chronic low back pain or fibromyalgia).

The secondary aim of the study is to estimate the effect size of the intervention on pain and function one month post-intervention, and to obtain data for sample-size calculation for a subsequent randomized controlled trial.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 to 65

Participation Criteria

Inclusion Criteria:

* French speaking
* Suffering from \[chronic low back pain OR fibromyalgia\] for \>6 months
* Average pain at least 4/10
* Central sensitization (assessed via a standardized physiotherapy evaluation and the Central Sensitization Inventory)

Exclusion Criteria:

* Health condition for which propranolol is contra-indicated
* Medication with which co-administration of propranolol is contra-indicated
* Severe or uncontrolled neurological/psychiatric condition (including post-traumatic stress disorder, substance abuse, suicidal ideation, etc.)
* Surgery of the lower-back in the last 3 years
* Litigation surrounding the painful condition

Study Location

Centre de recherche sur le vieillissement (CdRV)
Centre de recherche sur le vieillissement (CdRV)
Sherbrooke, Quebec
Canada

Contact Study Team

Primary Contact

Guillaume Leonard, Ph.D., pht.

CRCHUS: Centre de recherche du centre hospitalier universitaire de Sherbrooke
CRCHUS: Centre de recherche du centre hospitalier universitaire de Sherbrooke
Sherbrooke, Quebec
Canada

Contact Study Team

Primary Contact

Guillaume Leonard, PhD

[email protected]
(819) 821-8000
Study Sponsored By
Université de Sherbrooke
Participants Required
More Information
Study ID: NCT05085782