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Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia

Spastic Diplegia | Periventricular Leukomalacia

This is a randomized controlled trial, comparing 3 months of intensive leg exercise to standard physiotherapy care for the improvement of gross motor function in young children with spastic diplegia.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    1 to 3

Participation Criteria

Inclusion Criteria:

* Bilateral motor impairment of the lower extremities
* Periventricular white matter injury from encephalopathy of prematurity
* Able to stand with some support

Exclusion Criteria:

* Substantial upper extremity involvement - Manual Abilities Classification System (MACS) Level ≥3
* Uncontrolled epilepsy or infantile spasms in the past 6 months
* Cardiovascular or musculoskeletal complications that preclude participation in intensive exercise
* Botulinum toxin-A (BTX-A) injections in the legs in the last 6 months

Study Location

Alberta Children's Hospital
Alberta Children's Hospital
Calgary, Alberta
Canada

Contact Study Team

Primary Contact

Michelle Barnes, BScPT

[email protected]
780-492-4858
University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Michelle Barnes, BScPT

[email protected]
780-492-4858
Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: NCT03672877