DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery
Atrial Fibrillation | Atrial FlutterThis is a multicentre prospective cohort study where patients will receive up to 14 days of continuous ECG monitoring by wearing a portable monitoring device, starting within 72 hours after noncardiac surgery.
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Participation Requirements
-
Sex:
ALL -
Eligible Ages:
18 and up
Participation Criteria
Inclusion Criteria:
1. Had undergone noncardiac surgery within the past 72 hours and requiring, or expected to require, at least one of the following:
* an overnight hospital admission after surgery
* day surgery that would result in a large enough physiological insult to be able to cause POAF. Procedures excluded include those that are conducted using local anesthesia alone, are less than 30 minutes in duration, and/or are judged to be of low physiologic insult by the local investigator.
2. Have one of the following high-risk criteria;
* age 55-64 years, and having either established cardiovascular disease, recent major vascular surgery, a CHA2DS2-VASc score ≥3, or an elevated postoperative troponin level;
* age 65-74 years, and having either established cardiovascular disease, recent major vascular surgery, a CHA2DS2-VASc score ≥2, or an elevated postoperative troponin level; or
* age ≥75 years;
3. Provide written informed consent to participate.
Exclusion Criteria:
1. History of documented chronic (i.e., non-transient) AF before noncardiac surgery;
2. Need for long-term systemic anticoagulation;
3. Ongoing need for long-term dual antiplatelet treatment;
4. Contraindication to oral anticoagulation;
5. Severe renal insufficiency;
6. Severe liver cirrhosis;
7. Acute stroke in the past 14 days;
8. Underwent cardiac surgery in the past 35 days;
9. History of nontraumatic intracranial, intraocular, or spinal bleeding;
10. Hemorrhagic disorder or bleeding diathesis;
11. Known life expectancy \<1 year due to concomitant disease;
12. Women who are pregnant, breastfeeding, or of childbearing potential not taking effective contraception;
13. Expected to be non-compliant with follow-up and/or device use;
14. Known contact allergy to monitoring device and/or its peripheral components;
15. Previously enrolled in DETECT-POAF.
Study Location
Hamilton General Hospital
Hamilton General HospitalHamilton, Ontario
Canada
Contact Study Team
Mohamed Panju, MD
Niagara Health System - St. Catharine's Site
Niagara Health System - St. Catharine's SiteSt. Catharines, Ontario
Canada
Contact Study Team
Leonard Blair, MD
London Health Sciences Centre - University Hospital
London Health Sciences Centre - University HospitalLondon, Ontario
Canada
Contact Study Team
Marko Mrkobrada, MD
Hôpital Fleurimont du Centre hospitalier universitaire de Sherbrooke
Hôpital Fleurimont du Centre hospitalier universitaire de SherbrookeSherbrooke, Quebec
Canada
Contact Study Team
Félix Ayala-Paredes, MD
St. Joseph's Healthcare Hamilton
St. Joseph's Healthcare HamiltonHamilton, Ontario
Canada
Contact Study Team
Vikas Tandon, MD
Juravinski Hospital
Juravinski HospitalHamilton, Ontario
Canada
Contact Study Team
Ameen Patel, MD
- Study Sponsored By
- Population Health Research Institute
- Participants Required
- More Information
- Study ID:
NCT06519747