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PANDA Migraine: Pediatric vs Adult Neurochemistry Differences Across Migraine

Migraine | Headache | Brain | Adult | Children

This study looks at how migraines affect the brain at different ages. We will compare brain imaging of people with chronic migraine (at least 15 headache attack days/month) to those without and we want to compare children/youth and adults. This will help us find differences and similarities between adults and youth with migraine with the expectation that better understanding migraine will lead to better treatments in future. This study will have four groups: 1) children/youth (age 8-18y) with chronic migraine, 2) children/youth (age 8-18 y) without migraine, 3) adults (age 30-50y) with chronic migraine, and 4) adults (age 30-50y) without migraine.

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Participation Requirements

  • Sex:

    Male, Female, Intersex

  • Eligible Ages:

    7 to 50

Participation Criteria

Inclusion Criteria:
1) Children / youth aged 8-18 with and without migraines
2) Adults aged 30-50 with and without migraines
3) Ability to speak, understand, and read English

Exclusion Criteria:
You are not eligible to participate if you are:
1) significant medical comorbidity (i.e., epilepsy or arthritis)
2) significant global developmental delay or intellectual disability
3) Participants that have internal metallic devices that are not safe for MRI
4) Participants who may be pregnant

Study Location

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Study Sponsored By
University of Calgary
Participants Required
More Information
Study ID: REB25-0660