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Vascular Complications in Children From T1D Diagnosis

Type 1 Diabetes | Adolescent | Child | Cardiovascular Complications

Cardiovascular disease is a complication of type 1 diabetes (T1D), a life-long disease, usually diagnosed in childhood. The goal of this project is to determine the timing and factors leading to vascular damage in children from T1D diagnosis.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    8 to 17

Participation Criteria

Inclusion Criteria

1. Between the ages of 8-17 years
2. Within 14 weeks of type 1 diabetes diagnosis
3. Ability and willingness to undergo non-invasive arterial stiffness assessment for 1hr and willingness to wear the 24-h automated blood pressure monitoring (ABPM) device.

Exclusion Criteria

Children will be ineligible to participate in the study if they meet any of the following:

1. Other cardiometabolic or endocrine diseases diagnosis (type 2 diabetes; familial disorders of cholesterol metabolism; lupus)
2. Other genetic syndromes (Down Syndrome; Prader-Willi)
3. Eating disorder diagnosis
4. Transgender children taking hormone blockers or exogenous sex steroids
5. Currently treated with medications known to affect metabolism (e.g. glucocorticoids, antipsychotics).

Study Location

Endocrine and Diabetes Unit, BC Children's Hospital
Endocrine and Diabetes Unit, BC Children's Hospital
Vancouver, British Columbia
Canada

Contact Study Team

Primary Contact

Gemma Anderson

[email protected]
6048752000
Study Sponsored By
University of British Columbia
Participants Required
More Information
Study ID: NCT05790785