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Superior vs Temporal Laser Peripheral Iridotomy in Primary Angle Closure Suspects (PACS)

Primary Angle Glaucoma Closure Suspect

Basic Study Design: Prospective, randomized, single-center, single-blinded study to compare dysphotopsias and pain recollection immediately 2 weeks, and 3 months after LPI in PACS patients who have a clear indication for bilateral LPI. Our null hypothesis is that there is no difference in dysphotopsia or pain levels by LPI position. Our alternate hypothesis is that there are more dysphotopsias superiorly and more pain temporally.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

\* clinical evidence of bilateral occludable angles (PACS) defined as:

* Peripheral anterior synechia (PAS) absent and trabecular meshwork not visible in ≥6 clock hours under non-indentation gonioscopy, Along with,
* absence of PAC or PACG, in both eyes.
* macular and optic nerve OCT within the 95% range of the normative database for patients to be included in this study.

Exclusion Criteria:

* evidence of unilateral PACS,
* a history suggestive of an acute angle closure attack (based on symptoms) documented intraocular pressure over 30 mmHg,
* or any sign of Angle Closure Glaucoma (manifest glaucomatous neuropathy detected by OCT).
* Patients with previous ocular surgeries will also be excluded.

Study Location

Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Catherine Birt, MD, FRCSC

[email protected]
416-480-5882
Study Sponsored By
Sunnybrook Health Sciences Centre
Participants Required
More Information
Study ID: NCT04741919