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Comparing the effect of two spinal stimulation approaches to enhance hand and arm function after cervical spinal cord injury

Rehabilitation | Spinal Cord Injury | Electrical Stimulation

This study explores two promising therapies for restoring arm and hand function in people with chronic cervical spinal cord injury (SCI), a condition that affects independence and quality of life. It will compare transcutaneous spinal cord stimulation and paired corticospinal-motoneuronal stimulation, both combined with rehabilitation. Using a crossover design, participants will receive each therapy for two months, with a washout period in between. Safety, effectiveness, and patient-reported outcomes like daily living ability and quality of life will be assessed, alongside changes in neural excitability. Our goal is to tailor treatments to individual needs, promoting personalized care and improved outcomes.

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Participation Requirements

  • Sex:

    Any

  • Eligible Ages:

    18 to 75

Participation Criteria

Inclusion Criteria:
This study will include adults (age 18-75 years) with cervical (C3-C8 level) spinal cord injury that was sustained at least 9 months ago. Participants must be classified as American Spinal Injury Association Impairment Scale (AIS) B or C, meaning they may have some sensory and motor function below the level of injury or just some sensory function but no motor.
Exclusion Criteria:
Exclusion criteria include individuals with injury to the central nervous system other than spinal cord injury and individuals who are pregnant.

Study Location

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: Pro00149698