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Adjuncts for Adductor Block: Dexamethasone,Dexmedetomidine, or Combination to Reduce Pain

ACL Injury

The aim of this multi-centered study is to evaluate the effects of two distinct Adductor Canal Block (ACB) adjuncts, dexamethasone and dexmedetomidine, and their combination, on postoperative analgesia in patients undergoing Anterior Cruciate Ligament (ACL) Repair.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 to 50

Participation Criteria

Inclusion Criteria:

* English Speaking
* ASA 1-3 patients
* BMI \<40

Exclusion Criteria:

* Refusal or inability to provide informed consent
* Any contraindication to regional anesthesia including coagulopathy or bleeding diathesis, allergy to local anesthetics, infection, nerve injury or malignancy at the site of the block
* History of alcohol/drug dependence
* History of long term opioid intake or chronic pain disorder
* History of preexisting neuropathy in the operative leg
* History of significant psychiatric conditions that may affect patient assessment
* Inability to understand the informed consent and demands of the study
* Allergy to any of the components of the multimodal analgesic regimen
* Revision of ACL repair
* Diabetes
* Significant bradycardia (baseline heart rate ≤ 40 beats per minute)

Study Location

Women's College Hospital
Women's College Hospital
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Richard Brull, MD

[email protected]
416-323-6400
Backup Contact

Didem Bozak

[email protected]
416-323-6400
Study Sponsored By
Women's College Hospital
Participants Required
More Information
Study ID: NCT03643822