Optimal Number of Hyperbaric Oxygen Treatments for Carbon Monoxide Poisoning
Carbon Monoxide Poisoning | Hyperbaric Oxygen TherapyThe optimal treatment strategy with hyperbaric oxygen therapy has been the subject of some debate over the past 3 decades. Initial landmark studies showed a decrease in the incidence of DNS with a single treatment and also with three treatments over the course of 24 hours. These two strategies have continued to be used widely without further evidence comparing them in a direct fashion. Retrospective publications in the years since have been largely conflicting about the benefit of additional hyperbaric treatments. The investigators would seek to randomize patients with carbon monoxide poisoning to receive with 1 or 3 treatments with hyperbaric oxygen and measure their neurologic outcomes.
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Participation Requirements
-
Sex:
ALL -
Eligible Ages:
17 and up
Participation Criteria
Inclusion Criteria:
* All adult (over 17 years old) patients referred to a Hyperbaric Unit for acute carbon monoxide poisoning.
Exclusion Criteria:
* Obtunded
* Mechanically ventilated
* Pregnant
* Incarcerated
* Cognitively impaired (acutely or chronically)
Study Location
University of Alberta
University of AlbertaEdmonton, Alberta
Canada
Contact Study Team
- Study Sponsored By
- University of Alberta
- Participants Required
- More Information
- Study ID:
NCT06619717