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Studying the Effects of Cannabis on Vasculature

Cardiovascular Diseases | Inflammation | Atherosclerosis

Cannabis is commonly used globally. It is associated with psychiatric problems, but the effects on the cardiovascular system are unclear. In this project, the investigators plan to study the effects of cannabis on the cardiovascular system. This will be done by using a non-invasive test to measure blood vessel function and by using blood samples to measure inflammation. As a control for this project, the investigators would like to test the blood vessel function and inflammation levels of participants who do not use cannabis. This study will provide important information on the long term cardiovascular effects of cannabis.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    19 to 80

Participation Criteria

Inclusion Criteria:

* age: 19 to 80
* males and females
* all ethnicities
* cannabis use at least 3-4 times per week or more in the past 6 months (50 volunteers, experimental group)
* patients who do not use cannabis (50 volunteers, control group)
* no history of cardiovascular disease

Exclusion Criteria:

* that ingest cannabis containing cannabidiol (CBD)
* that are unable to provide a receipt for the cannabis product(s) they ingest
* that are unwilling to stop consuming soy products and/or genistein 48 hours prior to appointments.

Study Location

London Regional Health Science Centre
London Regional Health Science Centre
London, Ontario
Canada

Contact Study Team

Primary Contact

Mark Chandy, MD, PhD

Study Sponsored By
London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's
Participants Required
More Information
Study ID: NCT05581368