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Clinical Outcomes in Pediatric Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder (OCD) is a common neuropsychiatric illness beginning in childhood. Effective OCD treatments include cognitive-behaviour therapy (CBT) and medications but access to treatment is difficult and does not systematically include parents. The investigators will evaluate clinical and neural effects of Group-based Family CBT (GF-CBT), via a case-control study including: Group 1 - OCD cases receiving GF-CBT (N=90); Group 2 - OCD waitlist cases (N=90). Effects will be measured between baseline and completion of 12 GF-CBT sessions: comparing OCD severity and functioning changes between Groups 1 and 2.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    5 to 18

Participation Criteria

Inclusion Criteria:

* Male or female, aged 5-18 years old
* Ability of subject and parent to provide informed assent/consent
* English-speaking
* Current DSM IV-TR Axis I diagnosis of childhood-onset OCD; Moderate to severe OCD (CY-BOCS≥16/40)

Exclusion Criteria:

* Current diagnosis of bipolar disorder, psychosis, mental retardation or pervasive developmental disorder (e.g., autism), and current or past substance dependence/abuse

Study Location

BC Children's Hospital Research Institute
BC Children's Hospital Research Institute
Vancouver, British Columbia
Canada

Contact Study Team

Study Sponsored By
University of British Columbia
Participants Required
More Information
Study ID: NCT01635569