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Impact of Dairy Integration Into Canadian Food Guide on Gut Health

Gut and Circulating Inflammatory Markers | Gut Epithelial Permeability | Gut Microbiota Composition and...

The primary objective is to investigate the impact of milk, fermented milk, and soy beverages, incorporated in a diet reflecting adherence to Canadian food guide recommendations on food choices on gut microbiota in middle-aged adults (45-65 years) with abdominal obesity and slightly deteriorated lipids and/or glucose profile. The study aims to discern whether the integration of soy beverages (control), milk, and fermented milk within the CFG diet contributes to distinct gut outcomes and alterations in gut health. We hypothesized that milk and fermented milk will further promote beneficial changes in gut health parameters including gut microbiota composition, trans-epithelial permeability, and inflammation, relative to soy beverages.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    40 to 65

Participation Criteria

Inclusion Criteria:

* IMC \< 45
* Waist circumference \> 80 cm (Women) or 94 cm (men)

Exclusion Criteria:

* History of diabetes (types 1 and 2), CVD, enteropathy, immune diseases or bariatric surgery
* Cancer (diagnostic and/or treatment) during the last 5 years
* Antibiotic consumption during the last 3 months
* Active smoking or cannabis consumption
* Lactose intolerance or allergy, any allergies to foods given in the intervention phases
* Irregular defecation patterns
* Pregnancy/lactation
* Inability to speak French

Study Location

Institute of Nutrition and Functional Foods (INAF)
Institute of Nutrition and Functional Foods (INAF)
Québec, Quebec
Canada

Contact Study Team

Study Sponsored By
Laval University
Participants Required
More Information
Study ID: NCT07257913