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Lemborexant Treatment of Insomnia Linked to Epilepsy

Epilepsy | Sleep

The goal of this clinical trial is to assess whether Lemborexant can improve sleep in patients with epilepsy.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Sleep-related focal epilepsy
* Contraception

Exclusion Criteria:

* Changes in antiseizure medication 1 month before study protocol or during study protocol
* Concomitant medications per SUNRISE1
* Individuals with hepatic impairment
* Female participants who are pregnant or breastfeeding
* Individuals with compromised respiratory function
* Individuals with a history of complex sleep-related behaviour
* Individuals with rare hereditary diseases of galactose intolerance such as galactosemia or glucose-galactose malabsorption
* Individuals with a history of dependence or tolerance - abuse, dependence, rebound insomnia
* Individuals with psychiatric disorders with abnormal thinking and behavioural changes, depression, or suicidal ideation
* Individuals with a diagnosis of narcolepsy

Study Location

Health Sciences Centre
Health Sciences Centre
Winnipeg, Manitoba
Canada

Contact Study Team

Primary Contact

Marcus Ng, MD, FRCPC

[email protected]
204-787-2684
Study Sponsored By
University of Manitoba
Participants Required
More Information
Study ID: NCT06262594