cAPPricorn-1: A clinical trial for people living with Cerebral Amyloid Angiopathy (CAA)

Participation Requirements

• Sex:

  Male, Female, Intersex

• Eligible Ages:

  50 to 90

Participation Criteria

Inclusion Criteria:
There are 2 type of CAA: Sporadic CAA or Dutch-type CAA. You must have a diagnosis of either to participate.
In addition, specific to each type, people who can participate are people:
With Sporadic CAA who are:
-50 years of age or older
-Have recedived a diagnosis of CAA from their doctor

With Dutch-type CAA who are:
-30 years of age or older
-Have known gene mutation for Dutch-typeCAA

Additional criteria are assessed by the study team.

Exclusion Criteria:
People not eligible:
-People who have moderate to severe Alzheimer's disease
-History of previous intracranial bleeding (brain bleed) within 3 months
-no anti-platelet therapy or anti-coagulant therapy (blood thinners). Aspirin is allowed.
-must be able to have a lumbar puncture (spinal tap). No spinal problems.
-No significant heart problems
-No high blood pressure with a systolic greater than 150mmHg and diastolic greater than 90mmHg
-No attempted suicide

Other additional exclusions will be assessed by the study team