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The Predictive Value of Coexisting TMPRSS2-ERG Gene Fusion and PTEN Deletion in Prostate Cancer Patients with Biochemical Failure Status Post Salvage or Radical Radiation Therapy

Prostate Cancer

The objective of the study is to evaluate the predictive value of TMPRSS2-ERG gene fusion and PTEN in patients with high risk prostate cancer treated with first line LHRH agonist after biochemical failure.

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Participation Requirements

  • Sex:

    MALE

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* T3a +
* PSA \> 20
* Gleason 8 or higher
* Karnofsky performance status ≥ 70.
* Signed study-specific informed consent

Exclusion Criteria:

-

Study Location

CIUSSS du Saguenay-Lac-St-Jean/CSSS de Chicoutimi
CIUSSS du Saguenay-Lac-St-Jean/CSSS de Chicoutimi
Chicoutimi, Quebec
Canada

Contact Study Team

Primary Contact

Hugo Villeneuve, MD

Jewish General Hospital, McGill University
Jewish General Hospital, McGill University
Montreal, Quebec
Canada

Contact Study Team

Primary Contact

Ashley Feng, M.Sc.

[email protected]
514-340-8222
Backup Contact

Tamim Niazi, MD

CIUSSS de l'Est-de-l'Île-de-Montréal - Hôpital Maisonneuve-Rosemont
CIUSSS de l'Est-de-l'Île-de-Montréal - Hôpital Maisonneuve-Rosemont
Montreal, Quebec
Canada

Contact Study Team

Backup Contact

Peter Vavassis, MD

Primary Contact

Josée Abi-Saad

CIUSSS de la Mauricie-et-du-centre-du Quebec - Centre hospitalier régional de Trois-Rivières
CIUSSS de la Mauricie-et-du-centre-du Quebec - Centre hospitalier régional de Trois-Rivières
Trois-Rivières, Quebec
Canada

Contact Study Team

Backup Contact

Linda-Suzanne Vincent, MD

Primary Contact

Marie-Eve Caron

CISSS de la Montérégie-Centre - Hôpital Charles-LeMoyne
CISSS de la Montérégie-Centre - Hôpital Charles-LeMoyne
Greenfield Park, Quebec
Canada

Contact Study Team

Backup Contact

Marjorie Jolicoeur, MD

Primary Contact

Genevieve Bujold

MUHC - Cedars Cancer Center
MUHC - Cedars Cancer Center
Montreal, Quebec
Canada

Contact Study Team

Backup Contact

Luis Souhami, MD

Primary Contact

Marianna Perna

CISSS de Laval - Hôpital de la Cité-de-la-santé de Laval
CISSS de Laval - Hôpital de la Cité-de-la-santé de Laval
Laval, Quebec
Canada

Contact Study Team

Primary Contact

Solange Tremblay

Backup Contact

Levon Igidbashian, MD

CIUSSS de l'Estrie - Hôpital Fleurimont
CIUSSS de l'Estrie - Hôpital Fleurimont
Sherbrooke, Quebec
Canada

Contact Study Team

Primary Contact

Sophie Couture

Backup Contact

Abdenour Nabid, MD

Study Sponsored By
Sir Mortimer B. Davis - Jewish General Hospital
Participants Required
More Information
Study ID: NCT02573636