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A Comparison of Platelet Subtypes in Heart Attack Patients to Healthy Individuals

Heart Disease | Thrombosis | Coagulation | Heart Attack | Platelets | Blood

Platelets are cells that stop bleeding when an injury occurs. However, platelets can also form clots that obstruct the blood vessels of the heart leading to a heart attack.

Recently it has been discovered that different platelet subtypes exist based on the ability to produce a molecule called nitric oxide (NO). These different platelet subtypes have different roles in initiating and limiting how big a blood clot can grow. We want to compare the amount of NO producing platelets in patients who have recently suffered a heart attack to control healthy participants and are seeking a single 20 ml blood sample from healthy participants.

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Participation Requirements

  • Sex:

    Female, Intersex, Any, Male

  • Eligible Ages:

    18 to 80

Participation Criteria

Inclusion Criteria:
We seek to include in this study healthy adults either men or women that have between 18 to 80 years of age and in the case of the women should not be pregnant.
Exclusion Criteria:
Due to the nature of the study we can't include donors that have had a heart attack, have had a stroke, are currently taking medication to prevent a heart attack or a stroke such as aspirin, clopidogrel, prasugrel, or ticagrelor, have current diagnosis of diabetes, anemia, peripheral arterial disease (intense pain in the lower limbs when doing exercise), kidney disease, cancer, or a disease that decrease the platelet count in the blood.

Study Location

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Diego Castaneda Zaragoza

[email protected]
7802393558
Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: Pro00117362