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Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis

Scleroderma, Systemic | Digital Ulcer

This study is performed to consider the safety and healing ability of diosmin in patients with systemic sclerosis (scleroderma) and open sores on their fingers (digital ulcers). Two (2) out of three (3) participants will receive active product. The participants will have four (4) visits over eight (8) weeks. Physical exams and photos will be performed. A variety of questions will be asked describing level of pain and lifestyle changes.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

* Diagnosis of systemic sclerosis (scleroderma)
* At least one "active" digital ulcer
* Medication for systemic sclerosis unchanged for 30 days

Exclusion Criteria:

* Infection or gangrene in ulcer
* Citrus allergy
* Unstable heart, kidney, or liver disease
* Active infection of any type
* Current cancer treatment or uncured cancer
* Pregnancy or breast feeding

Study Location

Saint Joseph Health Care Centre
Saint Joseph Health Care Centre
London, Ontario
Canada

Contact Study Team

Backup Contact

Research Coordinator

[email protected]
(519) 646-6000
Primary Contact

Clinical Study Administrator

[email protected]
(519) 646-6100
Mount Sinai Health System
Mount Sinai Health System
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Director, Toronto Scleroderma Program

[email protected]
(416) 586-4800
Dalhousie University
Dalhousie University
Halifax, Nova Scotia
Canada

Contact Study Team

Backup Contact

Linehan

[email protected]
Primary Contact

Sutton, MD

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Primary Contact

Larche', MD

Backup Contact

Rebutoc

[email protected]
The Ottawa Hospital
The Ottawa Hospital
Ottawa, Ontario
Canada

Contact Study Team

Primary Contact

Maltez, MD

Study Sponsored By
Primus Pharmaceuticals
Participants Required
More Information
Study ID: NCT06256575