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Discovery of new extracellular vesicle-based diagnostic and predictive biomarker tests for Cardiac Disease

The development of new tests to diagnose and stratify cardiac disease remains one of the greatest unmet clinical needs in the field. This study aims to discover, develop, and validate “liquid biopsy” tests that are more sensitive, more accurate and more cost-effective than current tests for coronary artery disease.

This is a minimal risk, non-interventional study using blood samples from participants that have donated their specimens to different institutions for research. In this study we will evaluate the utility of novel tests to diagnose coronary artery disease and/or to predict treatment responses.

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Participation Requirements

  • Sex:

    Any

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:
1. Adult participant with or without CAD diagnosis
2. Willing to participate in the study or who have donated applicable biofluids for use in research
Exclusion Criteria:
1. Minor participant/volunteer
2. Unwilling or unable to provide informed consent to participate in the study
3. Participant under guardianship
4. Emergency surgery for unstable patients
5. Patients undergoing re-operative surgery
6. Patients with advanced heart failure defined by a Left Ventricular Ejection Fraction <40%

Study Location

University of Alberta
University of Alberta
Edmonton, Alberta
Canada

Contact Study Team

Primary Contact

Nassim Boroumand

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780-407-2667
Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: Pro00109766