Measures of Respiratory Health Registry

Participation Requirements

• Sex:

  ALL

• Eligible Ages:

  0 and up

Participation Criteria

Participants with CF

Inclusion Criteria:

-Diagnosis of CF as evidenced by one or more clinical feature consistent with the CF phenotype or positive CF newborn screen AND one or more of the following criteria: i. A documented sweat chloride ≥ 60 mEq/L by quantitative pilocarpine iontophoresis (QPIT).

ii. A documented genotype with two disease-causing mutations in the CFTR gene.

- In the opinion of the investigator, the participant will likely have the ability to perform the lung function test of interest on the day of testing

Exclusion Criteria:

* Physical findings at the screening that would compromise the safety of the participant or the quality of the data (e.g. respiratory distress or work of breathing)
* Requirement of supplementary oxygen to maintain oxygen saturation above 95%

Participants with other Respiratory Disease

Inclusion criteria:

* Physician-diagnosed lung disease
* Informed consent by participant, parent, or legal guardian
* In the opinion of the investigator, the participant will likely have the ability to perform the lung function test of interest on the day of testing

Exclusion criteria

* Physical findings at screening that would compromise the safety of the participant or the quality of the research data
* Requirement of supplementary oxygen to maintain oxygen saturation above 95%

Healthy Participants

* Inclusion criteria
* Informed consent by participant, parent, or legal guardian
* In the opinion of the investigator, the participant will likely have the ability to perform the lung function test of interest on the day of testing

Exclusion criteria

* Physical findings at screening that would compromise the safety of the participant or the quality of the research data
* Evidence of lung disease