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Scanning of Neurotransmitters in Children

Anxiety | Healthy Volunteers | Brain | Children | Anxiety Disorder

Anxiety is the most common childhood disorder, and it can have significant long-term outcomes when not successfully treated. One treatment limitation is poor understanding of what causes anxiety. This study uses a MRI scanner to measure a neurotransmitter system known as the noradrenergic system. The noradrenergic system works in the brain to help with attention, learning, sleep and anxiety. This study will compare this system children with a diagnosis of an anxiety disorder to those without a diagnosis of any anxiety disorder (healthy controls).

We will measure this system using MRI three times, spaced out across a year, to understand how this system is changing with time. As well as MRI, we will get measures of stress, cognition and behavior. We will look at how these relate to the noradrenergic system.

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Conditions de participation

  • Sexe:

    Male, Female, Intersex

  • Âges admissibles:

    8 to 12

Critères de participation

Inclusion Criteria:
Healthy cohort:
1) Aged between 8-12 years

Anxiety cohort:
1) Aged between 8-12 years
2) A diagnosis of an anxiety disorder by a health professional
Exclusion Criteria:
1) MRI safety contraindications such as implanted medical devices
2) Inability to read or understand English
3) Concussion within the past 3 months
4) A diagnosis of psychosis, autism, or intellectual disability
5) A diagnosis of a neurological disorder (epilepsy, stroke, cerebral palsy, brain tumor, etc.)

Lieu de l'étude

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contactez l'équipe d'étude

Étude parrainée par
University of Calgary
Participants recherchés
Plus d'informations
ID de l'étude: REB23-0808