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Cognition and dementia biomarkers in bipolar disorder

Bipolar Disorder | Brain | Cognition | Mood Swings | Alzheimer’s Disease

Preliminary research suggests that bipolar disorder and certain types of dementia may be linked. Dementia-related changes are not well understood in bipolar disorder and are difficult to disentangle from the symptoms of bipolar disorder itself. This study is designed to uncover whether certain cognitive tests may be useful as screening tools for early detection of dementia in individuals with bipolar disorder. We are examining this by looking at the relationships between these cognitive tests, dementia biomarkers, and dementia-associated genes in individuals with bipolar disorder.

If you choose to participate, you will be asked to:
1) Complete a series of questionnaires and pen-and-paper tasks designed to assess your thinking skills;
2) Have your blood drawn to look for specific biomarkers of neurodegenerative disease.

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Participation Requirements

  • Sex:

    Male, Female, Intersex

  • Eligible Ages:

    50 and up

Participation Criteria

Inclusion Criteria:
To participate in this study, you must:

1) Have a diagnosis of bipolar disorder
2) Currently have a stable, neutral mood
3) Be 50 years of age or older
4) Be fluent in written and oral English
5) Have normal or corrected-to-normal hearing and vision
Exclusion Criteria:
You cannot participate in this study if you have:

1) Had a stroke or brain injury
2) Severe dementia

Study Location

University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Study Sponsored By
University of Calgary
Participants Required
More Information
Study ID: REB20-0046