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Rapid MRI for Assessing Functional Abilities and Predicting TBI Outcomes

Traumatic Brain Injury

Our project aims to develop a rapidly acquired and communicated MRI assessment and report that incorporates functional and structural imaging to convey information about functional neurological insults following traumatic brain injury (TBI) that are not typically visible on clinical imaging. Within this framework, there are two sub-studies. The first is a prospective study of patients with TBI who will have an MRI in the sub-acute period after their injury, followed by clinical assessments up to 90 days post-injury. A model will be developed to link MRI biomarkers to persistent symptoms of TBI. The second sub-study will use a focus group methodology to develop the report content and format with input from several groups of stakeholders.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Sub-acute MRI study

Inclusion Criteria:

- Diagnosis of TBI

Exclusion Criteria:

* Self-reported history of brain surgery
* Self-reported history of major neurologic, psychiatric or substance use disorder
* Contraindications to MRI
* Inability to follow-up at 30 and 90 days

Focus group study Individuals with chronic TBI

Inclusion Criteria:

- Diagnosis of TBI greater than one year prior

Exclusion Criteria:

- Major neurologic, psychiatric or substance use disorder

Caregivers of individuals with chronic TBI

Inclusion Criteria:

- Relation who was diagnosed with TBI greater than one year prior that individual was the primary caregiver for

Exclusion Criteria:

- Major neurologic, psychiatric or substance use disorder

Clinicians who treat TBI

Inclusion Criteria:

- Employment as a physician or allied health professional who has spent greater than 50% of their time treating TBI patients for at least two years of their career

Exclusion Criteria:

-N/A

Inclusion Criteria:

- Employment as a personal injury lawyer or insurance adjuster who has spent greater than 50% of their time on TBI cases for at least two years of their career

Exclusion Criteria:

-N/A

Study Location

Queen's University
Queen's University
Kingston, Ontario
Canada

Contact Study Team

Primary Contact

DJ Cook

[email protected]
61354966666
University of Calgary
University of Calgary
Calgary, Alberta
Canada

Contact Study Team

Primary Contact

Chantel Debert

[email protected]
4032205110
Study Sponsored By
Queen's University
Participants Required
More Information
Study ID: NCT06454591