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Neurologic Physiology After Removal of Therapy (NeuPaRT)

Determination of Death

The purpose of this study is to determine when brain function stops compared to when the heart stops by monitoring electrical brain activity in patients who are taken off life support and progress to death in the intensive care unit.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

1. Age ≥ 18 years
2. Plan for the withdrawal of life sustaining measures (WLSM)
3. Attending physician anticipates patient will die within 24 hours of the withdrawal of life sustaining measures
4. Patient has an indwelling arterial cannula for monitoring blood pressure

Exclusion Criteria:

1. Brain death or plan for Neurologic Determination of Death (NDD)
2. Injuries that anatomically preclude the use of neurologic monitoring

Study Location

University of Calgary Foothills Campus
University of Calgary Foothills Campus
Calgary, Alberta
Canada

Contact Study Team

Backup Contact

Julie Kromm

Primary Contact

Andreas Kramer

Centre hospitalier de l'Université de Montréal,
Centre hospitalier de l'Université de Montréal,
Montréal, Quebec
Canada

Contact Study Team

Primary Contact

Michaël Chassé

Ottawa Hospital
Ottawa Hospital
Ottawa, Ontario
Canada

Contact Study Team

Backup Contact

Sonny Dhanani

Primary Contact

Shane English

Backup Contact

Tadeau Fantaneanu

Kingston Health Sciences Centre
Kingston Health Sciences Centre
Kingston, Ontario
Canada

Contact Study Team

Primary Contact

Gord Boyd

London Health Sciences Centre
London Health Sciences Centre
London, Ontario
Canada

Contact Study Team

Backup Contact

Marat Slessarev

[email protected]
519-685-8500
Primary Contact

Teneille Gofton

[email protected]
519-685-8500
Study Sponsored By
London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's
Participants Required
More Information
Study ID: NCT05306327