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Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment

Orthodontic Appliance Complication | White Spot Lesions | Smooth Surface Caries | Caries Arrested

Dental cavities are among the most frequent diseases that affect teeth, particularly in patients who are treated with braces due to the difficulty in maintaining good oral hygiene in the presence of the mouth appliances. The white spot lesion (WSL) is the first clinical sign of cavities that presents itself as a milky-white opacity when located on the front face of the tooth. The aim to manage these early lesions focuses on promoting natural remineralization and preventing further demineralization. Various materials have been introduced for management of WSLs including MI paste and MI paste combined with fluoride (MI paste plus). Recently, a new material called resin infiltration has been found to treat these lesions with high esthetic results and great performance. According to the few numbers of in-vivo studies investigating the effectiveness of remineralization products, the aim of the current study is to clinically compare the outcome of the resin-infiltration and etching + MI paste plus to stop and improve the appearance of the WSL on front teeth in patients after treatment with braces.

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    12 to 21

Participation Criteria

Inclusion Criteria:

* Individuals in the age range of 12-21 years who had undergone fixed orthodontic appliance therapy for a duration of 12-36 months.
* Should have at least one white spot lesion on the labial surface of either maxillary or mandibular anterior teeth after debonding. Lesion visible with or without drying the lesion surface.
* Patients with mild to moderate plaque accumulation. Fair oral hygiene. With a simplified Oral Hygiene Index of no more than 1.3-3.0

Exclusion Criteria:

* Poor oral hygiene Simplified Oral Hygiene Index of 3.1-6.0 or more
* Patients with hypoplasia or any developmental defects on the buccal of upper or lower incisors
* Patients with any restorations on the buccal of upper or lower incisors
* Patients that have presented WSL on the buccal of upper or lower incisors before orthodontic treatment was initiated.
* Patients that have received any re-mineralizing agent other than regular toothpaste during the last three months
* Patient with allergy to milk or any of their products
* Patient with any medical / oral or mental condition
* Patients or legal guardians that does not speak or read English

Study Location

KAYE Edmonton Clinic
KAYE Edmonton Clinic
Edmonton, Alberta
Canada

Contact Study Team

Backup Contact

Melanie Chouinard

[email protected]
780 407 5552
Primary Contact

Doris Lunardon, DDS

[email protected]
780 407 5572
Study Sponsored By
University of Alberta
Participants Required
More Information
Study ID: NCT05733676