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Nerve Grafting Technique to Preserve Erectile Function in Patients Undergoing Robotic Assisted Radical Prostatectomy

Prostate Cancer | Erectile Dysfunction

The investigator proposing a single arm prospective pilot trial evaluating the safety and the 1-year erectile recovery outcomes of patients undergoing Nerve Restoring (NR) Robotically assisted laparoscopic radical prostatectomy (RALP). During this study a total of 10 patients who are undergoing robotic prostatectomy will have their surgery performed utilizing a novel technique, NR-RALP, which incorporates a genitofemoral (GFN) nerve graft designed to try to improve the erectile function and recovery of men undergoing standard of care robotic prostatectomy while minimizing additional morbidity of the procedure

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Participation Requirements

  • Sex:

    MALE
  • Eligible Ages:

    18 and up

Participation Criteria

Inclusion Criteria:

1. Patients undergoing standard of care robotic radical prostatectomy for high-risk localized prostate cancer as defined by any of:

1. Gleason grade ≥8
2. PSA ≥20
3. \>pT2 on preoperative MRI imaging
2. Patients must have preoperative erectile function with a baseline IIEF score of ≥17

Exclusion Criteria:

1. Patients with previous pelvic surgery
2. Patients with previous pelvic radiotherapy
3. Patient with previous focal therapy for prostate cancer
4. Patients aged \< 18 years at diagnosis
5. Legally incapable patients
6. Patients who are unable to complete questionnaires and have no companion to help complete them
7. Patients undergoing a concomitant cancer surgery
8. Patients with pre-existing neurologic disease

Study Location

Jewish General Hospital, CIUSSS Centre-Ouest de l&#39;île de Montréal
Jewish General Hospital, CIUSSS Centre-Ouest de l&#39;île de Montréal
Montreal, Quebec
Canada

Contact Study Team

Primary Contact

Victor McPherson, MD

[email protected]
514-340-8222
Jewish General Hospital
Jewish General Hospital
Montréal, Quebec
Canada

Contact Study Team

Primary Contact

Victor McPherson, MD

[email protected]
514-340-8222
Backup Contact

Oleg Loutochin

[email protected]
514-340-8222
Study Sponsored By
Sir Mortimer B. Davis - Jewish General Hospital
Participants Required
More Information
Study ID: NCT06521710