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End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves

Neck Pain | Zygapophyseal Joint Arthritis

Aim of the EndPaRL study is to compare the efficacy and effectiveness of the two techniques utilizing sharp straight conventional radiofrequency needle with a trident needle for radiofrequency neurotomy of Cervical Medial Branch Nerves (CMBNs), in patients presenting with chronic, moderate-to-severe, neck pain due to cervical zygapophyseal joint osteoarthritis, as diagnosed by positive responses to two consecutive diagnostic blocks with local anesthetic of the CMBN.

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Participation Requirements

  • Sex:

    ALL
  • Eligible Ages:

    18 to 85

Participation Criteria

Inclusion Criteria:

1. Adult patient of either gender aged 18-85 years
2. Predominant axial (non-radicular) neck pain for at least 3 months
3. 7-day average NRS score for neck pain ≥ 5/10 at baseline evaluation
4. Moderate or greater functional impairment due to pain, defined as NDI Questionnaire raw score of 15 out of 50 (≥30% )e Failure to respond to conservative medical management (pharmacologic, physical therapy) for at least 3 months;

f) Positive response to two consecutive diagnostic blocks of the CMBN with a short and long-acting anesthetic

Exclusion Criteria:

1. Participants with financial incentives or litigation associated with ongoing pain
2. Inability to complete assessment instruments
3. Chronic widespread pain
4. Prior RFN of the CMBN;
5. Severe mental health issues
6. Pregnancy or other reason that precludes the use of fluoroscopy
7. Untreated coagulopathy
8. Systemic or local infection at the time of screening.

Study Location

University Health Network (UHN)
University Health Network (UHN)
Toronto, Ontario
Canada

Contact Study Team

Primary Contact

Danielle Alvares, PhD

[email protected]
416-603-5800
Women's College Hospital
Women's College Hospital
Toronto, Ontario
Canada

Contact Study Team

Backup Contact

Didem Bozak

[email protected]
(416) 323-6008
Primary Contact

Anuj Bhatia

[email protected]
(416) 603-5800
Study Sponsored By
University Health Network, Toronto
Participants Required
More Information
Study ID: NCT05818774