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Effects of Aerobic Exercise Intensity on Clinical & Neural Outcomes in Depressed Youth

Depression

This study will assess the effects of moderate vs. high intensity aerobic exercise, performed 3 times a week for 12 weeks under supervised conditions, on symptoms of depression, cognitive functioning and brain function in transitional aged youth (TAY: aged 16-24 years).

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Participation Requirements

  • Sex:

    ALL

  • Eligible Ages:

    16 to 24

Participation Criteria

Inclusion Criteria:

* Currently experiencing depression (MDD or PDD);
* Free of pharmacotherapy (ie. antidepressant medication) for \>5 weeks;
* Not currently engaging in regular moderate or vigorous intensity exercise;
* Able to read/understand English;
* Body mass index \[BMI\] \< 40;
* Medically cleared to engage in aerobic exercise.

Exclusion Criteria:

* Currently engaged in another exercise trial;
* Another Axis I/II DSM-5 disorder, apart from co-morbid anxiety disorder(s);
* Current or lifetime history of serious medical or neurological conditions;
* Currently taking psychoactive drugs (occasional use of anti-anxiety medication permitted);
* Regular user of nicotine products;
* Unstable medical conditions, especially those that prevent exercise;
* Exhibiting significant suicide risk;
* MRI contraindications;
* Currently pregnant or breastfeeding.

Study Location

University of Ottawa Institute of Mental Health Research
University of Ottawa Institute of Mental Health Research
Ottawa, Ontario
Canada

Contact Study Team

Primary Contact

Natalia Jaworska, PhD

[email protected]
613-722-6521
Study Sponsored By
The Royal's Institute of Mental Health Research
Participants Required
More Information
Study ID: NCT04110041